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Systematic review data and NICE guidelineĪntidepressants should be continued for at least six to 12 months after achieving treatment response to decrease the rate of relapse. SSRIs and SNRIs are recommended as first-line medications for treating GAD and PD. Systematic review, NICE guidelines, and USPSTF recommendation evaluating accuracy of tools but not on improving patient outcomes when used for screening There is insufficient evidence supporting universal screening for GAD in the general adult population. No consistent evidence currently supports a specific prevention strategy for PD or GAD, but exercise may be beneficial. Benzodiazepines are not recommended for first-line therapy or long-term use because of adverse reactions, risk of dependence, and higher mortality. Effective therapies for PD and GAD include cognitive behavior therapy and anti-depressants, including selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors. Anxiety disorders often present with substance use disorders, which should be treated concurrently. The GAD-7 and Patient Health Questionnaire for PD are validated screening tools that can aid in diagnosis and assessment. Although there is insufficient evidence to support universal screening for PD and GAD, evaluation should be considered in patients who express recurrent, pervasive worry or present with somatic symptoms not attributed to underlying medical conditions. Generalized anxiety disorder (GAD) and panic disorder (PD) are common mental health conditions in adults that are often seen in primary care.